Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.37 |
| ▸ | MEN1 | O00255 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5818112 | 0.90 | BCHE (0.38) | MAPTBCHEACHEGAAKMT2A | |
| SCHEMBL5796348 | 0.88 | MEN1 (0.41) | MAPTGLO1GAAKMT2AMEN1 | |
| SCHEMBL5799063 | 0.83 | RAB9A (0.48) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL5810724 | 0.83 | MAPT (0.41) | MAPTGLO1BCHEACHEGAA | |
| SCHEMBL5810719 | 0.83 | MAPT (0.41) | MAPTGLO1BCHEACHEGAA | |
| SCHEMBL5799059 | 0.82 | NPC1 (0.39) | MAPTGLO1GAAKMT2AMEN1 | |
| SCHEMBL5796715 | 0.81 | MAPT (0.46) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL5823657 | 0.81 | ALDH1A1 (0.46) | MAPTGLO1KMT2AMEN1ALDH1A1 | |
| SCHEMBL5798801 | 0.78 | HDAC1 (0.38) | KMT2AMEN1ACP1 | |
| SCHEMBL5822231 | 0.77 | KMT2A (0.48) | MAPTGAAKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |