Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PNKP | Q96T60 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5796946 | 0.91 | MTNR1A (0.43) | ALDH1A1KMT2ARAB9AMAPTLMNA | |
| SCHEMBL5797676 | 0.87 | HDAC6 (0.42) | MAPTHPGDHTTCYP2C9CYP2C19 | |
| SCHEMBL5799923 | 0.87 | GCGR (0.43) | ALDH1A1KMT2ARAB9AMAPTLMNA | |
| SCHEMBL5795637 | 0.86 | HDAC1 (0.37) | ALDH1A1KMT2ARAB9AMAPTLMNA | |
| SCHEMBL5799659 | 0.85 | MTNR1A (0.41) | ALDH1A1KMT2ARAB9AMAPTLMNA | |
| SCHEMBL5796765 | 0.84 | MAPT (0.41) | ALDH1A1KMT2ARAB9AMAPTMEN1 | |
| SCHEMBL5799126 | 0.84 | PTGER4 (0.44) | ALDH1A1KMT2ARAB9AMAPTLMNA | |
| SCHEMBL5799059 | 0.84 | NPC1 (0.39) | ALDH1A1KMT2ARAB9AMAPTMEN1 | |
| SCHEMBL5797554 | 0.83 | P2RX3 (0.47) | KMT2ARAB9AMAPTLMNAMEN1 | |
| SCHEMBL5799447 | 0.82 | HDAC6 (0.43) | ALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |