Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | GRK2 | P25098 | 1/20 | 0.38 |
| ▸ | GRK5 | P34947 | 1/20 | 0.38 |
| ▸ | GRK3 | P35626 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5796946 | 0.93 | MTNR1A (0.43) | MTNR1AMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5799923 | 0.91 | GCGR (0.43) | MTNR1AMAPTMEN1KMT2AKDM4E | |
| SCHEMBL5799640 | 0.88 | MAPT (0.52) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5799682 | 0.85 | NPC1 (0.39) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL5823657 | 0.85 | ALDH1A1 (0.46) | MTNR1AMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5796765 | 0.83 | MAPT (0.41) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5822231 | 0.83 | KMT2A (0.48) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5799741 | 0.82 | ALDH1A1 (0.40) | MAPTKMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL5797676 | 0.80 | HDAC6 (0.42) | MAPTCYP2C9CYP2C19MCL1 | |
| SCHEMBL5797642 | 0.79 | HDAC6 (0.44) | MAPTMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |