Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 4/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.44 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.44 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11771733 | 0.93 | LTA4H (0.46) | LTA4HGRIN1GRIN2BSMN1; SMN2KDM4E | |
| SCHEMBL1723556 | 0.84 | TAAR1 (0.48) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11105345 | 0.81 | ALDH1A1 (0.44) | LTA4HHPGDALDH1A1CYP2D6ATM | |
| SCHEMBL13611378 | 0.80 | LTA4H (0.46) | LTA4HRAB9ANPC1SMN1; SMN2TDP1 | |
| SCHEMBL6210283 | 0.80 | LTA4H (0.51) | LTA4HGRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL10905429 | 0.79 | LTA4H (0.47) | LTA4HGRIN1GRIN2BSMN1; SMN2L3MBTL1 | |
| SCHEMBL4081720 | 0.77 | TAAR1 (0.41) | MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL11961679 | 0.77 | TAAR1 (0.41) | MEN1KMT2ARAB9ANPC1TP53 | |
| SCHEMBL10424271 | 0.76 | LTA4H (0.44) | LTA4HSMN1; SMN2KDM4EHPGDALDH1A1 | |
| SCHEMBL4439445 | 0.76 | ALDH1A1 (0.51) | LTA4HSMN1; SMN2KDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7115748-B2 | Method of making imidazole-2-thiones | ALLERGAN, INC. (US) | 2006-10-03 | — | — | US | disclosed |
| WO-2006062890-A1 | METHOD OF MAKING IMIDAZOLE-2-THIONES | ALLERGAN, INC. (US) | 2006-06-15 | — | — | WO | disclosed |
| US-20060122400-A1 | Method of making imidazole-2-thiones | ALLERGAN, INC. | 2006-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122400-A1 | Method of making imidazole-2-thiones | TST, INMT, TPMT | LTA4H 3249/4885GRIN1 2688/4885GRIN2B 1411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.