Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.31 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7262159 | 0.87 | LMNA (0.39) | CRHR1LMNAALDH1A1PDE2AKMT2A | |
| SCHEMBL5802072 | 0.85 | MAPK1 (0.34) | CRHR1ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL4819474 | 0.83 | ALDH1A1 (0.34) | CRHR1LMNAALDH1A1PDE2AKMT2A | |
| SCHEMBL4819838 | 0.83 | ALDH1A1 (0.34) | CRHR1LMNAALDH1A1PDE2AKMT2A | |
| SCHEMBL5936228 | 0.83 | CRHR1 (0.38) | CRHR1LMNAALDH1A1PDE2AKMT2A | |
| SCHEMBL5802390 | 0.82 | CRHR1 (0.34) | CRHR1LMNAALDH1A1KMT2AMBOAT4 | |
| SCHEMBL5802573 | 0.81 | ALDH1A1 (0.35) | CRHR1LMNAALDH1A1PDE2AKMT2A | |
| SCHEMBL3174833 | 0.80 | LMNA (0.36) | CRHR1LMNAALDH1A1PDE2AKMT2A | |
| SCHEMBL5799864 | 0.80 | GAA (0.36) | CRHR1LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL3180998 | 0.80 | LMNA (0.38) | LMNAALDH1A1PDE2AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006066874-A1 | NOVEL TRIAZOLOPYRIMIDINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-06-29 | — | — | WO | disclosed |