SCHEMBL7262159

SCHEMBL7262159

CC(C)Nc1c(-c2c(F)cccc2Cl)c(Cl)nc2ncnn12

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.39
ALDH1A1 P00352 4/20 0.37
ENPP1 P22413 1/20 0.36
PDE2A O00408 1/20 0.36
TSHR P16473 2/20 0.35
HPGD P15428 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
GAA P10253 2/20 0.35
CRHR1 P34998 1/20 0.35
POLB P06746 1/20 0.34
GFER P55789 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8389574 0.90 ENPP1 (0.43) LMNAALDH1A1ENPP1PDE2ATSHR
SCHEMBL5936228 0.89 CRHR1 (0.38) LMNAALDH1A1ENPP1PDE2ATSHR
SCHEMBL4819474 0.89 ALDH1A1 (0.34) LMNAALDH1A1ENPP1PDE2ATSHR
SCHEMBL4819838 0.89 ALDH1A1 (0.34) LMNAALDH1A1ENPP1PDE2ATSHR
SCHEMBL3180998 0.88 LMNA (0.38) LMNAALDH1A1PDE2ATSHRHPGD
SCHEMBL3176097 0.87 LMNA (0.36) LMNAALDH1A1PDE2ATSHRHPGD
SCHEMBL3174928 0.87 LMNA (0.38) LMNAALDH1A1PDE2ATSHRHPGD
SCHEMBL5799748 0.87 CRHR1 (0.35) LMNAALDH1A1ENPP1PDE2ATSHR
SCHEMBL4814986 0.86 ALDH1A1 (0.38) LMNAALDH1A1TSHRHPGDSMN1; SMN2
SCHEMBL3174833 0.86 LMNA (0.36) LMNAALDH1A1PDE2ATSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6656944-B2 Synergistc mixtures BASF AKTIENGESELLSCHAFT (DE) 2003-12-02 US claimed
US-20020111380-A1 Fungicidal mixtures BASF AKTIENGESELLSCHAFT (DE) 2002-08-15 US claimed
US-6656944-B2 Synergistc mixtures BASF AKTIENGESELLSCHAFT (DE) 2003-12-02 US disclosed
US-20020111380-A1 Fungicidal mixtures BASF AKTIENGESELLSCHAFT (DE) 2002-08-15 US disclosed
US-6268371-B1 Fungicidal mixtures AMERICAN CYANAMID CO. 2001-07-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020111380-A1 Fungicidal mixtures TYR, MAOA, PMM2 LMNA 2701/4885ALDH1A1 376/4885ENPP1 221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.