Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.33 |
| ▸ | CHRNG | P07510 | 1/20 | 0.33 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5819926 | 0.98 | L3MBTL1 (0.37) | PTGS2L3MBTL1PDE4BHSD11B1CNR1 | |
| SCHEMBL5797992 | 0.91 | LMNA (0.39) | HSD11B1ALDH1A1KDM4ECYP19A1CHRNB2 | |
| SCHEMBL5798160 | 0.90 | L3MBTL1 (0.37) | PTGS2L3MBTL1PDE4BHSD11B1CNR1 | |
| SCHEMBL5822711 | 0.90 | LMNA (0.39) | HSD11B1ALDH1A1KDM4ECHRNB2SLC6A2 | |
| SCHEMBL5798701 | 0.90 | PTGS2 (0.45) | PTGS2CYP19A1 | |
| SCHEMBL5800554 | 0.89 | PTGS2 (0.38) | PTGS2HSD11B1ALDH1A1CYP19A1SLC6A3 | |
| SCHEMBL5560260 | 0.89 | PTGS2 (0.37) | PTGS2HSD11B1ALDH1A1CYP19A1 | |
| SCHEMBL5819680 | 0.88 | PTGS2 (0.37) | PTGS2CYP19A1 | |
| SCHEMBL5800837 | 0.88 | L3MBTL1 (0.37) | PTGS2L3MBTL1PDE4BHSD11B1CNR1 | |
| SCHEMBL5559333 | 0.88 | PTGS2 (0.43) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |