Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | TACR3 | P29371 | 5/20 | 0.31 |
| ▸ | TACR2 | P21452 | 3/20 | 0.31 |
| ▸ | TACR1 | P25103 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | USP14 | P54578 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5822674 | 0.98 | PTGS2 (0.36) | PTGS2CYP19A1PDE2ATACR3TACR2 | |
| SCHEMBL5800554 | 0.94 | PTGS2 (0.38) | PTGS2CYP19A1AKR1C3AKR1C2TSHR | |
| SCHEMBL5800295 | 0.92 | TSHR (0.36) | PTGS2CYP19A1AKR1C3AKR1C2TSHR | |
| SCHEMBL5560260 | 0.92 | PTGS2 (0.37) | PTGS2CYP19A1FAAHMGLL | |
| SCHEMBL5558388 | 0.91 | PTGS2 (0.35) | PTGS2CYP19A1AKR1C3AKR1C2FAAH | |
| SCHEMBL5798701 | 0.90 | PTGS2 (0.45) | PTGS2CYP19A1AKR1C3AKR1C2 | |
| SCHEMBL5822558 | 0.89 | PTGS2 (0.34) | PTGS2CYP19A1PDE2ATACR3TACR2 | |
| SCHEMBL5800993 | 0.88 | PTGS2 (0.37) | PTGS2CYP19A1 | |
| SCHEMBL5559333 | 0.88 | PTGS2 (0.43) | PTGS2AKR1C3AKR1C2 | |
| SCHEMBL5819926 | 0.86 | L3MBTL1 (0.37) | PTGS2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |