Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | DBH | P09172 | 1/20 | 0.33 |
| ▸ | ICMT | O60725 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31265751 | 0.98 | TUBB1 (0.35) | TUBB1PDGFRBPDGFRADBHICMT | |
| SCHEMBL14639852 | 0.79 | TUBB1 (0.37) | TUBB1PDGFRBPDGFRADBHICMT | |
| SCHEMBL4946568 | 0.74 | ACHE (0.52) | TUBB1HTR2AHTR2CHTR2BACHE | |
| SCHEMBL14600840 | 0.74 | TDP1 (0.37) | TUBB1PDGFRBPDGFRADBHICMT | |
| SCHEMBL21995716 | 0.74 | ALDH1A1 (0.41) | ALDH1A1GAA | |
| SCHEMBL11714686 | 0.73 | HDAC1 (0.40) | ALDH1A1TDP1 | |
| SCHEMBL3450618 | 0.73 | PDGFRB (0.37) | TUBB1PDGFRBPDGFRADBHALDH1A1 | |
| Hydrochloric Acid SCHEMBL9526742 | 0.73 | ALDH1A1 (0.47) | TUBB1KDM4EALDH1A1GAATAAR1 | |
| Hydrochloric Acid SCHEMBL28015515 | 0.73 | ACHE (0.50) | PDGFRBPDGFRAHTR2AHTR2CHTR2B | |
| SCHEMBL28699193 | 0.73 | CA2 (0.46) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |
| US-20050234244-A1 | Synthesis of COX-2 and FAAH inhibitors | IRONWOOD PHARMACEUTICALS, INC. | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234244-A1 | Synthesis of COX-2 and FAAH inhibitors | FAAH2, FAAH, PTGES2 | TUBB1 2692/4885PDGFRB 1558/4885PDGFRA 1530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.