Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 6/20 | 0.57 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.57 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5802232 | 0.99 | ADRA1A (0.56) | ADRA1AADRA1BADRA1DHTR1A | |
| SCHEMBL5800584 | 0.87 | HTR1A (0.62) | ADRA1AADRA1BADRA1DHTR1A | |
| Hydrochloric Acid SCHEMBL5801035 | 0.86 | HTR1A (0.61) | ADRA1AADRA1BADRA1DHTR1A | |
| SCHEMBL5801012 | 0.85 | DRD2 (0.53) | ADRA1AADRA1BADRA1DHTR1A | |
| Hydrochloric Acid SCHEMBL5800862 | 0.84 | DRD2 (0.52) | ADRA1AADRA1BADRA1DHTR1A | |
| SCHEMBL5155682 | 0.83 | HTR1A (0.66) | ADRA1AADRA1BADRA1DHTR1A | |
| Hydrochloric Acid SCHEMBL6406987 | 0.83 | ADRA1A (0.66) | ADRA1AADRA1BADRA1DHTR1A | |
| SCHEMBL5592278 | 0.82 | HTR1A (0.68) | ADRA1AADRA1BADRA1DHTR1A | |
| SCHEMBL5801015 | 0.81 | HTR1A (0.44) | ADRA1AADRA1BADRA1DHTR1A | |
| Hydrochloric Acid SCHEMBL5592228 | 0.81 | HTR1A (0.67) | ADRA1AADRA1BADRA1DHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006051399-A1 | PIPERAZINE DERIVATIVES USEFUL AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-05-18 | — | — | WO | claimed |
| WO-2006051399-A1 | PIPERAZINE DERIVATIVES USEFUL AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-05-18 | — | — | WO | disclosed |