Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.44 |
| ▸ | HTR7 | P34969 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5803588 | 0.99 | ALDH1A1 (0.46) | HTR1AHTR7ALDH1A1TSHRMAPK1 | |
| SCHEMBL5810923 | 0.84 | RAB9A (0.42) | HTR1AHTR7ALDH1A1TSHRMAPK1 | |
| SCHEMBL5800584 | 0.84 | HTR1A (0.62) | HTR1AHTR7MEN1CYP1A2CYP2C9 | |
| SCHEMBL4522960 | 0.83 | HTR1A (0.61) | HTR1AHTR7MEN1CYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL5801035 | 0.83 | HTR1A (0.61) | HTR1AHTR7ALDH1A1MEN1CYP1A2 | |
| SCHEMBL5592219 | 0.83 | HTR7 (0.64) | HTR1AHTR7ALDH1A1MEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL4524619 | 0.83 | HTR1A (0.60) | HTR1AHTR7MEN1CYP1A2CYP2C9 | |
| SCHEMBL5801012 | 0.82 | DRD2 (0.53) | HTR1AHTR7ALDH1A1HTTMEN1 | |
| Hydrochloric Acid SCHEMBL5592239 | 0.82 | HTR7 (0.62) | HTR1AHTR7ALDH1A1MEN1CYP1A2 | |
| SCHEMBL5801216 | 0.81 | ADRA1A (0.57) | HTR1AADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006051399-A1 | PIPERAZINE DERIVATIVES USEFUL AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-05-18 | — | — | WO | claimed |
| WO-2006051399-A1 | PIPERAZINE DERIVATIVES USEFUL AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-05-18 | — | — | WO | disclosed |