Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 8/20 | 0.41 |
| ▸ | HRH1 | P35367 | 8/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 5/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | CA9 | Q16790 | 5/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.35 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2013987 | 0.82 | MAPT (0.49) | HRH2HRH1CA12CA1CA2 | |
| SCHEMBL2009205 | 0.77 | SMN1; SMN2 (0.51) | CA12CA1CA2CA9 | |
| SCHEMBL2014794 | 0.76 | L3MBTL1 (0.40) | HRH2HRH1L3MBTL1CA12CA1 | |
| SCHEMBL8377749 | 0.74 | CA12 (0.44) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL3604860 | 0.73 | RAB9A (0.49) | CA12CA1CA2CA9 | |
| SCHEMBL2013045 | 0.72 | SMN1; SMN2 (0.49) | L3MBTL1POLBPLA2G4B | |
| SCHEMBL1295614 | 0.71 | PLA2G4B (0.52) | CA12CA1CA2CA9PLA2G4B | |
| Methenamine SCHEMBL5801339 | 0.71 | EPHX2 (0.48) | HRH2HRH1CA12CA1CA2 | |
| SCHEMBL16215508 | 0.71 | ALDH1A1 (0.55) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL882755 | 0.69 | HDAC1 (0.44) | L3MBTL1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1677783-A2 | FIBRINOGEN RECEPTOR ANTAGONISTS AND THEIR USE | Nicholas Piramal India Limited (IN) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005035495-A2 | FIBRINOGEN RECEPTOR ANTAGONISTS AND THEIR USE | NICHOLAS PIRAMAL INDIA LIMITED (IN) | 2005-04-21 | — | — | WO | disclosed |