Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5788516 | 0.79 | HRH3 (0.67) | HRH3HRH4NCF1LTA4HALDH1A1 | |
| SCHEMBL5790680 | 0.79 | HRH3 (0.67) | HRH3HRH4NCF1LTA4HALDH1A1 | |
| SCHEMBL5788519 | 0.79 | HRH3 (0.67) | HRH3HRH4NCF1LTA4HALDH1A1 | |
| SCHEMBL12383 | 0.67 | ALDH1A1 (0.55) | HRH3HRH4ALDH1A1KDM4E | |
| SCHEMBL10872018 | 0.67 | DRD2 (0.38) | KDM4E | |
| SCHEMBL10691883 | 0.66 | SIGMAR1 (0.52) | ALDH1A1KDM4E | |
| SCHEMBL9163392 | 0.66 | KDM4E (0.53) | HRH3HRH4ALDH1A1KDM4E | |
| SCHEMBL4148981 | 0.66 | KDM4E (0.53) | HRH3HRH4ALDH1A1KDM4E | |
| SCHEMBL22711368 | 0.66 | KDM4E (0.53) | HRH3HRH4ALDH1A1KDM4E | |
| SCHEMBL12156566 | 0.66 | KDM4E (0.53) | HRH3HRH4ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720847-A1 | HISTAMINE-3 RECEPTOR MODULATORS | Pfizer Products Incorporated (US) | 2006-11-15 | — | — | EP | claimed |
| WO-2005080361-A1 | HISTAMINE-3 RECEPTOR MODULATORS | PFIZER PRODUCTS INC. (US) | 2005-09-01 | — | — | WO | claimed |