Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.38 |
| ▸ | DRD4 | P21917 | 10/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691883 | 0.82 | SIGMAR1 (0.52) | DRD2DRD4KDM1AKDM4EHTT | |
| SCHEMBL9820772 | 0.70 | NPC1 (0.44) | — | |
| SCHEMBL10685814 | 0.69 | SIGMAR1 (0.39) | KDM1AKDM4EHTTLMNAGAA | |
| SCHEMBL10694936 | 0.68 | SIGMAR1 (0.40) | KDM4EHTTLMNAGAATDP1 | |
| SCHEMBL10682744 | 0.68 | SIGMAR1 (0.38) | KDM1AKDM4EHTTLMNAGAA | |
| SCHEMBL5802152 | 0.67 | HRH3 (0.44) | KDM4E | |
| SCHEMBL10929087 | 0.66 | SIGMAR1 (0.69) | KDM4EHTTLMNAGAA | |
| SCHEMBL10929081 | 0.66 | SIGMAR1 (0.69) | KDM4EHTTLMNAGAA | |
| SCHEMBL9821040 | 0.61 | FFAR1 (0.55) | — | |
| SCHEMBL9821161 | 0.61 | ALDH1A1 (0.42) | HTTLMNAGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0188887-A1 | Tertiary amine compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-07-30 | — | — | EP | disclosed |