Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.52 |
| ▸ | EBP | Q15125 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | DRD4 | P21917 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10872018 | 0.82 | DRD2 (0.38) | KDM1ADRD2DRD4KDM4EHTT | |
| SCHEMBL10685814 | 0.76 | SIGMAR1 (0.39) | SIGMAR1EBPADORA3CHRM1DRD3 | |
| SCHEMBL10682744 | 0.75 | SIGMAR1 (0.38) | SIGMAR1EBPADORA3CHRM1DRD3 | |
| SCHEMBL11099523 | 0.73 | SIGMAR1 (0.68) | SIGMAR1EBPADORA3CHRM1DRD3 | |
| SCHEMBL9820846 | 0.71 | HRH3 (0.47) | SIGMAR1EBPKCNH2HSD17B10SLC6A2 | |
| SCHEMBL5801186 | 0.71 | HTR2C (0.49) | HTR2CKDM1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9820788 | 0.71 | HTR2C (0.49) | HTR2CKDM1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10700544 | 0.70 | SIGMAR1 (0.44) | SIGMAR1EBPADORA3CHRM1DRD3 | |
| SCHEMBL10699792 | 0.70 | SIGMAR1 (0.47) | SIGMAR1EBPADORA3CHRM1DRD3 | |
| SCHEMBL11399593 | 0.69 | SIGMAR1 (0.51) | SIGMAR1EBPADORA3CHRM1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251466-A2 | Chemical process for the preparation of esters of substituted cyclopropyl caboxylic acids | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-01-07 | — | — | EP | disclosed |
| EP-0188887-A1 | Tertiary amine compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-07-30 | — | — | EP | disclosed |