Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.45 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.45 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL216931 | 1.00 | ALDH1A1 (0.46) | ALDH1A1TDP1CYP3A4TSHRMAPT | |
| SCHEMBL31165708 | 0.80 | SMN1; SMN2 (0.46) | ALDH1A1TDP1CYP3A4TSHRMAPT | |
| SCHEMBL6589360 | 0.80 | TXNRD1 (0.49) | ALDH1A1TDP1CYP3A4TSHRMAPT | |
| SCHEMBL2978051 | 0.80 | HSD17B10 (0.46) | ALDH1A1TDP1CYP3A4TSHRMAPT | |
| SCHEMBL4040996 | 0.80 | SMN1; SMN2 (0.46) | ALDH1A1TDP1CYP3A4TSHRMAPT | |
| SCHEMBL12868738 | 0.76 | TXNRD1 (0.41) | ALDH1A1TDP1CYP3A4TSHRMAPT | |
| SCHEMBL6770996 | 0.76 | ALDH1A1 (0.47) | ALDH1A1TDP1CYP3A4MAPTKDM4E | |
| SCHEMBL6587072 | 0.76 | VCAM1 (0.43) | ALDH1A1TDP1CYP3A4TSHRMAPT | |
| Hydrochloric Acid SCHEMBL6770644 | 0.75 | ALDH1A1 (0.46) | ALDH1A1TDP1CYP3A4MAPTKDM4E | |
| SCHEMBL11208894 | 0.75 | MAPT (0.59) | ALDH1A1MAPTG6PDTLR9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115044226-A | 3-amino-5-nitrobenzoisothiazole-based dye and preparation method thereof | 金塔县晋泰森新材料科技有限公司 | 2022-09-13 | — | — | CN | claimed |
| CN-114989088-A | Meta-aramid fiber color development method and used treating agent | 浙江理工大学 | 2022-09-02 | — | — | CN | claimed |
| CN-114836997-A | In-situ coupling color development method of meta-aramid and obtained color development aramid | 浙江理工大学 | 2022-08-02 | — | — | CN | claimed |
| WO-2006058338-A2 | 4 - PIPERIDINECARBOXAMIDE DERIVATIVES AS MODULATORS OF VANILLOID VR1 RECEPTOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-06-01 | — | — | WO | claimed |
| US-20060116368-A1 | 4-Piperidinecarboxamide modulators of vanilloid VR1 receptor | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-06-01 | — | — | US | claimed |
| EP-4658264-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USE TO INHIBIT PROTEIN AGGREGATION | Purdue Research Foundation (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163907-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USE TO INHIBIT PROTEIN AGGREGATION | PURDUE RESEARCH FOUNDATION (US) | 2024-08-08 | — | — | WO | disclosed |
| CN-114989088-A | Meta-aramid fiber color development method and used treating agent | 浙江理工大学 | 2022-09-02 | — | — | CN | disclosed |
| CN-114836997-A | In-situ coupling color development method of meta-aramid and obtained color development aramid | 浙江理工大学 | 2022-08-02 | — | — | CN | disclosed |
| US-20060116368-A1 | 4-Piperidinecarboxamide modulators of vanilloid VR1 receptor | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-06-01 | — | — | US | disclosed |
| WO-2006058338-A2 | 4 - PIPERIDINECARBOXAMIDE DERIVATIVES AS MODULATORS OF VANILLOID VR1 RECEPTOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-06-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116368-A1 | 4-Piperidinecarboxamide modulators of vanilloid VR1 receptor | VDAC1, TRPV1, HVCN1 | ALDH1A1 1117/4885TDP1 4229/4885CYP3A4 1405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.