Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29225355 | 0.72 | ALDH1A1 (0.48) | KDM4EL3MBTL1MAPK1HTTKMT2A | |
| SCHEMBL29225354 | 0.72 | CYP19A1 (0.52) | KDM4EMAPK1HPGDLMNAHTT | |
| SCHEMBL11384661 | 0.72 | HTR3A (0.50) | HTR3AHTT | |
| SCHEMBL13281350 | 0.71 | HTT (0.49) | KDM4ELMNAHTTKMT2A | |
| SCHEMBL4965091 | 0.71 | KDM4E (0.46) | KDM4EL3MBTL1PRMT5WDR77SLC6A2 | |
| SCHEMBL4962479 | 0.70 | CARM1 (0.48) | SLC6A2HTR2AHTR2CSLC6A4HTR7 | |
| SCHEMBL61112 | 0.69 | CTSL (0.56) | CHRM2CHRM1CHRNB2CHRM3CHRNA4 | |
| SCHEMBL9131464 | 0.69 | CTSL (0.56) | CHRM2CHRM1CHRNB2CHRM3CHRNA4 | |
| SCHEMBL8606746 | 0.69 | HRH4 (0.47) | HTR3A | |
| SCHEMBL10972132 | 0.69 | MAOA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006073938-A2 | METHOD FOR THE SYNTHESIS OF 3-SUBSTITUTED INDOLIZINE AND BENZOINDOLIZINE COMPOUNDS | EAST CAROLINA UNIVERSITY (US) | 2006-07-13 | — | — | WO | disclosed |