Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5807728 | 0.89 | NPSR1 (0.41) | PKMNPSR1F10ALDH1A1SMN1; SMN2 | |
| SCHEMBL5322077 | 0.81 | ADRA1A (0.52) | TDP1ADRA1AADRB2ADRB1HTR1A | |
| SCHEMBL10642171 | 0.76 | PKM (0.51) | PKMADRA1AADRB2ADRB1HTR1A | |
| SCHEMBL5059304 | 0.75 | ADRA1D (0.56) | PKMTDP1ADRA1AADRB2ADRB1 | |
| SCHEMBL5059309 | 0.75 | ADRA1D (0.56) | PKMTDP1ADRA1AADRB2ADRB1 | |
| SCHEMBL5804284 | 0.75 | MEN1 (0.50) | HTTALDH1A1SMN1; SMN2POLBHPGD | |
| SCHEMBL31411917 | 0.74 | ALDH1A1 (0.57) | PKMNPSR1F10ALDH1A1SMN1; SMN2 | |
| SCHEMBL10642055 | 0.74 | ALDH1A1 (0.57) | PKMNPSR1F10ALDH1A1SMN1; SMN2 | |
| SCHEMBL10842372 | 0.72 | ACHE (0.52) | NPSR1ALDH1A1CA1CA2ACHE | |
| SCHEMBL10842678 | 0.72 | ACHE (0.52) | NPSR1ALDH1A1CA1CA2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006070285-A2 | ENZYMATIC PREPARATION OF AN INTERMEDIATE COMPOUND FOR THE SYNTHESIS OF TAMSULOSIN | QUIMICA SINTETICA, S.A. (ES) | 2006-07-06 | — | — | WO | disclosed |