Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5811165 | 0.90 | CYP1A2 (0.42) | MPOCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5810951 | 0.87 | CYP1A2 (0.48) | MPOCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5806654 | 0.85 | MPO (0.42) | MPOCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5809111 | 0.84 | CNR2 (0.49) | MPOCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5811682 | 0.81 | MAOA (0.47) | MPOCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5809748 | 0.79 | CNR1 (0.40) | MPOCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5806157 | 0.78 | ABCB1 (0.43) | CYP1A2CYP3A4CYP2C9CYP2C19RAB9A | |
| Hydrochloric Acid SCHEMBL5811001 | 0.78 | CNR1 (0.39) | MPOCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5807542 | 0.78 | HTR6 (0.54) | MPOCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5807474 | 0.77 | CYP1A2 (0.41) | CYP1A2CYP3A4CYP2C9CYP2C19NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025717-A1 | PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | claimed |
| WO-2006025717-A1 | PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | disclosed |