Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.65 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.65 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.65 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.65 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.65 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.58 |
| ▸ | F13A1 | P00488 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4074353 | 0.85 | HDAC3 (0.87) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL7765076 | 0.84 | L3MBTL1 (0.79) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL13073412 | 0.83 | HDAC3 (0.78) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL696928 | 0.82 | HDAC3 (0.62) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL4153733 | 0.82 | HPGD (0.79) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL11186772 | 0.82 | HDAC3 (0.62) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL2186352 | 0.82 | HDAC2 (0.72) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL13619739 | 0.82 | HDAC3 (0.62) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL17117356 | 0.81 | HDAC1 (0.79) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL6426559 | 0.81 | HDAC3 (0.60) | HDAC3HDAC1HDAC2HDAC10HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093518-A2 | THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | APATH, LLC (US) | 2006-09-08 | — | — | WO | disclosed |