Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11364006 | 0.92 | ALDH1A1 (0.45) | ALDH1A1GAAHPGDKDM4EMAPT | |
| SCHEMBL5823974 | 0.86 | HMGCR (0.46) | GAAKDM4EMAPTTP53 | |
| SCHEMBL28662576 | 0.80 | MAPT (0.44) | ALDH1A1GAAHPGDKDM4EMAPT | |
| SCHEMBL4163228 | 0.78 | PTGS2 (0.40) | DHODHPTGS2ALDH1A1KDM4EMAPT | |
| SCHEMBL2644649 | 0.77 | MAPK14 (0.58) | MAPK14 | |
| SCHEMBL23146756 | 0.76 | GRIA2 (0.40) | DHODHALDH1A1GAAMAPT | |
| SCHEMBL20568219 | 0.76 | DHODH (0.43) | DHODHALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL29722929 | 0.75 | SMN1; SMN2 (0.61) | PTGS2ALDH1A1GAAMAPT | |
| SCHEMBL2662802 | 0.74 | MAPK14 (0.55) | ALDH1A1GAAHPGDKDM4EMAPT | |
| SCHEMBL23348207 | 0.74 | GCGR (0.46) | ALDH1A1HPGDKDM4EMAPTMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006110918-A1 | PYRROLE COMPOUNDS AND USES THEREOF | AMBIT BIOSCIENCES CORPORATION (US) | 2006-10-19 | — | — | WO | disclosed |