Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CCR6 | P51684 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1361191 | 0.76 | — | — | |
| SCHEMBL401985 | 0.74 | KMT2A (0.36) | MEN1LMNAKMT2AMAPTRAB9A | |
| SCHEMBL1568988 | 0.73 | DRD1 (0.32) | MEN1LMNAKMT2ADRD1ALDH1A1 | |
| SCHEMBL1034447 | 0.73 | HRH4 (0.30) | MEN1LMNAKMT2AMAPT | |
| SCHEMBL1638099 | 0.71 | MAPT (0.34) | MEN1LMNAKMT2AMAPTDRD1 | |
| SCHEMBL17923137 | 0.71 | CRHR1 (0.35) | MEN1LMNAKMT2AMAPTRAB9A | |
| SCHEMBL11283982 | 0.71 | KMT2A (0.33) | MEN1LMNAKMT2AMAPTRAB9A | |
| SCHEMBL15409375 | 0.70 | ALOX15 (0.33) | MEN1LMNAKMT2AMAPTRAB9A | |
| SCHEMBL2006272 | 0.70 | ALDH1A1 (0.44) | MEN1LMNAKMT2AMAPTRAB9A | |
| SCHEMBL10697500 | 0.70 | HSD17B10 (0.44) | MEN1LMNAKMT2AMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6506784-B1 | Inhibiting pest Gamma aminobutyric acid receptors by contacting said receptors with a compound of methods of controlling pests, especially insects and arachnids such as fleas and ticks | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2003-01-14 | — | — | US | claimed |
| US-5177100-A | Pesticides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-01-05 | — | — | US | claimed |
| WO-2006097279-A1 | AMIDRAZONE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF AKTIENGESELLSCHAFT (DE) | 2006-09-21 | — | — | WO | disclosed |
| US-6506784-B1 | Inhibiting pest Gamma aminobutyric acid receptors by contacting said receptors with a compound of methods of controlling pests, especially insects and arachnids such as fleas and ticks | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2003-01-14 | — | — | US | disclosed |