SCHEMBL5809079

SCHEMBL5809079

O=C(O)Cc1ccc2c(OCc3ccccc3)c(CC(=O)O)ccc2c1OCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER1 P34995 2/20 0.48
PTGER4 P35408 2/20 0.48
PTGER3 P43115 2/20 0.48
PTGER2 P43116 2/20 0.48
FABP4 P15090 1/20 0.48
FABP5 Q01469 1/20 0.48
AKR1B1 P15121 2/20 0.47
THRA P10827 1/20 0.47
THRB P10828 1/20 0.47
ALDH1A1 P00352 3/20 0.45
USP2 O75604 1/20 0.45
TSHR P16473 1/20 0.45
HSD17B10 Q99714 1/20 0.45
LMNA P02545 1/20 0.44
HPGD P15428 1/20 0.44
FFAR1 O14842 1/20 0.44
FFAR4 Q5NUL3 1/20 0.44
CFD P00746 1/20 0.44
PLG P00747 1/20 0.44
PLAU P00749 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5113606 0.88 TDP1 (0.53) PTGER1PTGER4PTGER3PTGER2FABP4
SCHEMBL16862344 0.81 PTPN1 (0.60) PTGER1PTGER4PTGER3PTGER2FABP4
SCHEMBL6036164 0.81 FABP4 (0.52) PTGER1PTGER4PTGER3PTGER2FABP4
SCHEMBL10591847 0.81 FABP4 (0.72) PTGER1PTGER4PTGER3PTGER2FABP4
SCHEMBL15610227 0.81 AKR1B1 (0.58) PTGER1PTGER4PTGER3PTGER2FABP4
SCHEMBL6034976 0.80 FABP4 (0.66) PTGER1PTGER4PTGER3PTGER2FABP4
SCHEMBL6036276 0.80 CXCL8 (0.51) PTGER1PTGER4PTGER3PTGER2FABP4
SCHEMBL6036130 0.80 THRA (0.54) PTGER1PTGER4PTGER3PTGER2FABP4
SCHEMBL31664052 0.80 THRA (0.54) PTGER1PTGER4PTGER3PTGER2FABP4
SCHEMBL10963748 0.77 POLB (0.50) PTGER1PTGER4PTGER3PTGER2FABP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006107644-A1 COLORANT COMPOUNDS, INTERMEDIATES, AND COMPOSITIONS MILLIKEN & COMPANY (US) 2006-10-12 WO disclosed
US-20060223993-A1 Colorant compounds, intermediates, and compositions MILLIKEN & COMPANY 2006-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060223993-A1 Colorant compounds, intermediates, and compositions AAAS, TST, AADAC PTGER1 616/4885PTGER4 282/4885PTGER3 403/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.