Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 2/20 | 0.66 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.66 |
| ▸ | CXCL8 | P10145 | 3/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.51 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.51 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.51 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TTR | P02766 | 2/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.49 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.49 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.49 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17130535 | 0.88 | FABP4 (0.52) | FABP4FABP5PTGER1PTGER4PTGER3 | |
| SCHEMBL15610227 | 0.83 | AKR1B1 (0.58) | FABP4FABP5PTGER1PTGER4PTGER3 | |
| SCHEMBL6036164 | 0.83 | FABP4 (0.52) | FABP4FABP5PTGER1PTGER4PTGER3 | |
| SCHEMBL10591847 | 0.83 | FABP4 (0.72) | FABP4FABP5PTGER1PTGER4PTGER3 | |
| SCHEMBL6036276 | 0.82 | CXCL8 (0.51) | FABP4FABP5CXCL8PTGER1PTGER4 | |
| SCHEMBL6036130 | 0.82 | THRA (0.54) | FABP4FABP5PTGER1PTGER4PTGER3 | |
| SCHEMBL31664052 | 0.82 | THRA (0.54) | FABP4FABP5PTGER1PTGER4PTGER3 | |
| SCHEMBL12117432 | 0.81 | HTR1A (0.49) | FABP4FABP5PTGER1PTGER4PTGER3 | |
| SCHEMBL16685000 | 0.80 | AKR1B1 (0.51) | FABP4FABP5KMT2ATHRATHRB | |
| SCHEMBL21295168 | 0.80 | HTR1A (0.61) | KMT2AADRA1APTGS1PTGS2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060148858-A1 | 1, 2-Azole derivatives with hypoglycemic and hypolipidemic activity | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148858-A1 | 1, 2-Azole derivatives with hypoglycemic and hypolipidemic activity | GPR119, SLC5A1, CYP4B1 | FABP4 279/4885FABP5 2065/4885CXCL8 4247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.