Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 14/20 | 0.46 |
| ▸ | CTSS | P25774 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15247712 | 0.86 | CTSK (0.49) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL12011309 | 0.83 | CA1 (0.44) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL8975300 | 0.81 | APLNR (0.40) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL8041100 | 0.81 | CA1 (0.55) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL16063760 | 0.80 | CA2 (0.44) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL5154942 | 0.80 | CA1 (0.53) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL464207 | 0.80 | CA1 (0.41) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL12011310 | 0.80 | CTSK (0.43) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL12194532 | 0.79 | REN (0.43) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL12195057 | 0.79 | CTSK (0.43) | CTSKCTSSCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006086609-A2 | INHIBITORS OF TRYPTASE | AXYS PHARMACEUTICALS, INC. (US) | 2006-08-17 | — | — | WO | disclosed |