Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5811663 | 1.00 | CA12 (0.40) | CA12CA7CA9CA14ALDH1A1 | |
| SCHEMBL5794195 | 1.00 | CA12 (0.40) | CA12CA7CA9CA14ALDH1A1 | |
| SCHEMBL6560435 | 0.90 | CA12 (0.43) | CA12CA7CA9CA14ALDH1A1 | |
| SCHEMBL5808979 | 0.90 | PPID (0.45) | ALDH1A1MAPTLMNAHDAC2HDAC8 | |
| SCHEMBL5795342 | 0.90 | PPID (0.45) | ALDH1A1MAPTLMNAHDAC2HDAC8 | |
| SCHEMBL5808973 | 0.90 | PPID (0.45) | ALDH1A1MAPTLMNAHDAC2HDAC8 | |
| SCHEMBL6454131 | 0.88 | CA12 (0.42) | CA12CA7CA14NPC1MAPT | |
| SCHEMBL4075370 | 0.87 | MMP12 (0.42) | ALDH1A1NPC1RAB9ASLC13A5GAA | |
| SCHEMBL4075367 | 0.87 | MMP12 (0.42) | ALDH1A1NPC1RAB9ASLC13A5GAA | |
| SCHEMBL5885751 | 0.86 | MEN1 (0.44) | ALDH1A1NPC1MAPTRAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006128590-A1 | HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | DSM IP ASSETS B.V. (NL) | 2006-12-07 | — | — | WO | claimed |
| WO-2006128590-A1 | HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | DSM IP ASSETS B.V. (NL) | 2006-12-07 | — | — | WO | disclosed |