Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5808973 | 1.00 | PPID (0.45) | PPIDLMNAMMP8ALOX5ABCB1 | |
| SCHEMBL5795342 | 1.00 | PPID (0.45) | PPIDLMNAMMP8ALOX5ABCB1 | |
| SCHEMBL5794195 | 0.90 | CA12 (0.40) | LMNAALDH1A1MAPTHDAC3HDAC4 | |
| SCHEMBL5811663 | 0.90 | CA12 (0.40) | LMNAALDH1A1MAPTHDAC3HDAC4 | |
| SCHEMBL5809381 | 0.90 | CA12 (0.40) | LMNAALDH1A1MAPTHDAC3HDAC4 | |
| SCHEMBL4074798 | 0.89 | PPID (0.46) | PPIDALOX5ABCB1SMN1; SMN2MAPT | |
| SCHEMBL5885751 | 0.89 | MEN1 (0.44) | LMNAALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL6454131 | 0.86 | CA12 (0.42) | MAPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4075370 | 0.85 | MMP12 (0.42) | LMNASMN1; SMN2ALDH1A1HDAC3HDAC4 | |
| SCHEMBL4075367 | 0.85 | MMP12 (0.42) | LMNASMN1; SMN2ALDH1A1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006128590-A1 | HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | DSM IP ASSETS B.V. (NL) | 2006-12-07 | — | — | WO | claimed |
| WO-2006128590-A1 | HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | DSM IP ASSETS B.V. (NL) | 2006-12-07 | — | — | WO | disclosed |