Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5808973 | 0.89 | PPID (0.45) | TDP1ALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL5808979 | 0.89 | PPID (0.45) | TDP1ALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL5795342 | 0.89 | PPID (0.45) | TDP1ALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL5809381 | 0.86 | CA12 (0.40) | NPC1RAB9ATDP1ALDH1A1GAA | |
| SCHEMBL5794195 | 0.86 | CA12 (0.40) | NPC1RAB9ATDP1ALDH1A1GAA | |
| SCHEMBL5811663 | 0.86 | CA12 (0.40) | NPC1RAB9ATDP1ALDH1A1GAA | |
| SCHEMBL6454131 | 0.83 | CA12 (0.42) | NPC1RAB9ACTSKMAPT | |
| SCHEMBL4075367 | 0.82 | MMP12 (0.42) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL4075370 | 0.82 | MMP12 (0.42) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL6560435 | 0.79 | CA12 (0.43) | NPC1RAB9ATDP1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7041845-B2 | Process for preparing optically active dihydropyrones | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2006-05-09 | — | — | US | disclosed |
| US-20040133032-A1 | Process for preparing optically active dihydropyrones | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040133032-A1 | Process for preparing optically active dihydropyrones | CYP3A5, CYP3A43, CYP3A4 | MEN1 2701/4885KMT2A 3236/4885NPC1 2645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.