Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5808979 | 1.00 | PPID (0.45) | PPIDLMNAMMP8ALOX5ABCB1 | |
| SCHEMBL5808973 | 1.00 | PPID (0.45) | PPIDLMNAMMP8ALOX5ABCB1 | |
| SCHEMBL5794195 | 0.90 | CA12 (0.40) | LMNAALDH1A1MAPTHDAC3HDAC4 | |
| SCHEMBL5811663 | 0.90 | CA12 (0.40) | LMNAALDH1A1MAPTHDAC3HDAC4 | |
| SCHEMBL5809381 | 0.90 | CA12 (0.40) | LMNAALDH1A1MAPTHDAC3HDAC4 | |
| SCHEMBL4074798 | 0.89 | PPID (0.46) | PPIDALOX5ABCB1SMN1; SMN2MAPT | |
| SCHEMBL5885751 | 0.89 | MEN1 (0.44) | LMNAALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL6454131 | 0.86 | CA12 (0.42) | MAPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4075370 | 0.85 | MMP12 (0.42) | LMNASMN1; SMN2ALDH1A1HDAC3HDAC4 | |
| SCHEMBL4075367 | 0.85 | MMP12 (0.42) | LMNASMN1; SMN2ALDH1A1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006128590-A1 | HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | DSM IP ASSETS B.V. (NL) | 2006-12-07 | — | — | WO | claimed |
| EP-1572620-B1 | METHOD FOR THE PRODUCTION OF OPTICALLY ACTIVE DIHYDROPYRONES | BOEHRINGER INGELHEIM PHARMA (DE) | 2013-10-23 | — | — | EP | disclosed |
| WO-2006128590-A1 | HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | DSM IP ASSETS B.V. (NL) | 2006-12-07 | — | — | WO | disclosed |
| US-7041845-B2 | Process for preparing optically active dihydropyrones | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2006-05-09 | — | — | US | disclosed |
| WO-2006006851-A2 | PROCESS FOR THE PREPARATION OF AN ENANTIOMERICALLY ENRICHED ESTER OR THE CORRESPONDING ACID THEREOF | DSM IP ASSETS B.V. (NL) | 2006-01-19 | — | — | WO | disclosed |
| EP-1572620-A2 | METHOD FOR THE PRODUCTION OF OPTICALLY ACTIVE DIHYDROPYRONES | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2005-09-14 | — | — | EP | disclosed |
| US-20040133032-A1 | Process for preparing optically active dihydropyrones | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-07-08 | — | — | US | disclosed |
| WO-2004052831-A2 | METHOD FOR THE PRODUCTION OF OPTICALLY ACTIVE DIHYDROPYRONES | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040133032-A1 | Process for preparing optically active dihydropyrones | CYP3A5, CYP3A43, CYP3A4 | PPID 2244/4885LMNA 1403/4885MMP8 4732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.