Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | SLC13A5 | Q86YT5 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4075370 | 1.00 | MMP12 (0.42) | MMP12SLC13A5KDM4EMEN1LMNA | |
| SCHEMBL4071793 | 0.88 | SLC13A5 (0.49) | SLC13A5KDM4EMEN1LMNACYP1A2 | |
| SCHEMBL6696645 | 0.88 | SLC13A5 (0.49) | SLC13A5KDM4EMEN1LMNACYP1A2 | |
| SCHEMBL4071789 | 0.88 | SLC13A5 (0.49) | SLC13A5KDM4EMEN1LMNACYP1A2 | |
| SCHEMBL5809381 | 0.87 | CA12 (0.40) | SLC13A5KDM4ELMNAGAAALOX12 | |
| SCHEMBL5794195 | 0.87 | CA12 (0.40) | SLC13A5KDM4ELMNAGAAALOX12 | |
| SCHEMBL5811663 | 0.87 | CA12 (0.40) | SLC13A5KDM4ELMNAGAAALOX12 | |
| SCHEMBL5808973 | 0.85 | PPID (0.45) | LMNAHDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL5808979 | 0.85 | PPID (0.45) | LMNAHDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL5795342 | 0.85 | PPID (0.45) | LMNAHDAC2HDAC8HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481961-B1 | PROCESS FOR PRODUCING (R)-3-HYDROXY-3-(2-PHENYLETHYL)HEXANOIC ACID AND ITS INTERMEDIATE | SUMITOMO CHEMICAL CO (JP) | 2009-11-25 | — | — | EP | disclosed |
| CN-100528828-C | Production method of racemiation3-hydroxy-3- (2-phenylethyl) hexanoic acid C1-6 alkyl ester | SUMIKA FINE CHEMICALS CO LTD (JP) | 2009-08-19 | — | — | CN | disclosed |
| EP-1894912-B1 | Process for producing racemic 3-hydroxy-3-(2-phenylethyl) hexanoic acid ester | SUMITOMO CHEMICAL CO (JP) | 2009-08-05 | — | — | EP | disclosed |
| EP-1894912-A1 | Process for producing racemic 3-hydroxy-3-(2-phenylethyl) hexanoic acid ester | Sumitomo Chemical Company, Limited (JP) | 2008-03-05 | — | — | EP | disclosed |
| CN-1982284-A | Production method of (R) -3 hydroxy-3- (2-phenylethyl) hexanoic acid and intermediate thereof | SUMIKA FINE CHEMICALS CO LTD (JP) | 2007-06-20 | — | — | CN | disclosed |
| CN-1301244-C | Process for producing -3-hydroxy-3- (2-phenylethyl) hexanoic acid and intermediates thereof | SUMITOMO CHEMICAL CO (JP) | 2007-02-21 | — | — | CN | disclosed |
| US-7038075-B2 | Production method of racemic 3-hydroxy-3-(2-phenylethyl)hexanoic acid C1-6 alkyl ester | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-05-02 | — | — | US | disclosed |
| WO-2006006851-A2 | PROCESS FOR THE PREPARATION OF AN ENANTIOMERICALLY ENRICHED ESTER OR THE CORRESPONDING ACID THEREOF | DSM IP ASSETS B.V. (NL) | 2006-01-19 | — | — | WO | disclosed |
| CN-1617846-A | Process for producing -3-hydroxy-3- (2-phenylethyl) hexanoic acid and intermediates thereof | SUMITOMO CHEMICAL CO (JP) | 2005-05-18 | — | — | CN | disclosed |
| EP-1481961-A1 | PROCESS FOR PRODUCING (R)-3-HYDROXY-3-(2-PHENYLETHYL)HEXANOIC ACID AND ITS INTERMEDIATE | Sumitomo Chemical Company, Limited (JP) | 2004-12-01 | — | — | EP | disclosed |
| US-20040138496-A1 | Production method of (R)-3- hydroxy-3-(2-phenylethyl)hexanoic acid and intermediate thereof | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2004-07-15 | — | — | US | disclosed |
| US-6683207-B2 | RESOLUTION USING 1-AMINO-1-PHENYLETHANE DERIVATIVE | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2004-01-27 | — | — | US | disclosed |
| US-20030176507-A1 | Production method of (R) -3 hydroxy-3- (2-phenylethyl) hexanoic acid and intermediate thereof | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2003-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138496-A1 | Production method of (R)-3- hydroxy-3-(2-phenylethyl)hexanoic acid and intermediate thereof | HAAO, HPD, HAO2 | MMP12 4528/4885SLC13A5 403/4885KDM4E 2546/4885 |
| US-20030176507-A1 | Production method of (R) -3 hydroxy-3- (2-phenylethyl) hexanoic acid and intermediate thereof | HAAO, HPD, HAO2 | MMP12 4432/4885SLC13A5 586/4885KDM4E 2381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.