Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6109551 | 0.83 | KDM4E (0.51) | MEN1KMT2AADORA2AADORA1HSD17B10 | |
| SCHEMBL5805731 | 0.80 | LMNA (0.62) | PDE4BPDE4DMEN1KMT2AADORA2A | |
| SCHEMBL6112336 | 0.80 | ADORA2A (0.50) | MEN1KMT2AADORA2AADORA1HPGD | |
| SCHEMBL6110296 | 0.78 | KDM4E (0.38) | PDE4BPDE4DKMT2AADORA2AADORA1 | |
| SCHEMBL1321790 | 0.78 | NPSR1 (0.37) | PDE4BPDE4DMEN1KMT2AADORA2A | |
| SCHEMBL6111192 | 0.76 | ALDH1A1 (0.52) | MEN1KMT2AADORA2AADORA1HSD17B10 | |
| SCHEMBL5809819 | 0.75 | L3MBTL1 (0.44) | MEN1KMT2AADORA2AADORA1HSD17B10 | |
| SCHEMBL27429230 | 0.73 | ADORA1 (0.60) | PDE4BPDE4DMEN1KMT2AADORA2A | |
| SCHEMBL1320853 | 0.72 | L3MBTL1 (0.68) | MEN1KMT2AADORA2AADORA1HSD17B10 | |
| SCHEMBL19313821 | 0.71 | ADORA1 (0.52) | MEN1KMT2AADORA2AADORA1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006100095-A1 | SUBSTITUTED CARBOXAMIDES METHOD FOR PRODUCTION AND USE THEREOF AS TNF-ALPHA RELEASE INHIBITORS | CURACYTE DISCOVERY GMBH (DE) | 2006-09-28 | — | — | WO | disclosed |