Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | GPR3 | P46089 | 1/20 | 0.54 |
| ▸ | KIF11 | P52732 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28335170 | 0.90 | ALDH1A1 (0.59) | AHRALDH1A1HSD17B10KIF11KDM4E | |
| SCHEMBL29844524 | 0.90 | ALDH1A1 (0.59) | AHRALDH1A1HSD17B10KIF11KDM4E | |
| SCHEMBL2311195 | 0.85 | AHR (0.53) | AHRALDH1A1HSD17B10GPR3KIF11 | |
| SCHEMBL19768708 | 0.82 | AHR (0.59) | AHRALDH1A1HSD17B10GPR3KIF11 | |
| SCHEMBL1734811 | 0.81 | AHR (0.57) | AHRALDH1A1HSD17B10GPR3KIF11 | |
| SCHEMBL30196772 | 0.81 | AHR (0.57) | AHRALDH1A1HSD17B10GPR3KIF11 | |
| SCHEMBL27835129 | 0.81 | AHR (0.57) | AHRALDH1A1HSD17B10GPR3KIF11 | |
| SCHEMBL4812375 | 0.81 | KIF11 (0.79) | AHRALDH1A1HSD17B10GPR3KIF11 | |
| SCHEMBL22089502 | 0.81 | AHR (0.57) | AHRALDH1A1HSD17B10GPR3KIF11 | |
| SCHEMBL6615916 | 0.80 | KDM4E (0.54) | AHRALDH1A1HSD17B10GPR3KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106543147-B | A kind of substituted carbazole-imidazole salts or benzimidazole salt compound and preparation method thereof | 云南大学 | 2019-07-19 | — | — | CN | disclosed |
| US-8772311-B2 | Harmine derivatives, intermediates used in their preparations, preparation processes and use thereof | XINJIANG HUASHIDAN PHARMACEUTICAL RESEARCH CO., LTD. (CN) | 2014-07-08 | — | — | US | disclosed |
| US-8772311-B2 | Harmine derivatives, intermediates used in their preparations, preparation processes and use thereof | XINJIANG HUASHIDAN PHARMACEUTICAL RESEARCH CO., LTD. (CN) | 2014-07-08 | — | — | US | disclosed |
| US-20090227619-A1 | Harmine derivatives, intermediates used in their preparations, preparation processes and use therefo | XINJIANG HUASHIDAN PHARMACEUTICAL RESEARCH CO., LTD. (CN) | 2009-09-10 | — | — | US | disclosed |
| US-20090227619-A1 | Harmine derivatives, intermediates used in their preparations, preparation processes and use therefo | XINJIANG HUASHIDAN PHARMACEUTICAL RESEARCH CO., LTD. (CN) | 2009-09-10 | — | — | US | disclosed |
| WO-2006012310-A2 | CARBAZOLE DERIVATIVES FOR TREATING POLYCYSTIC KIDNEY DISEASE | GENZYME CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227619-A1 | Harmine derivatives, intermediates used in their preparations, preparation processes and use therefo | TPH1, HTR1F, TPH2 | AHR 366/4885ALDH1A1 324/4885HSD17B10 1360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.