Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 11/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 10/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.51 |
| ▸ | PIP5K1C | O60331 | 5/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.46 |
| ▸ | PIP5K1B | O14986 | 2/20 | 0.46 |
| ▸ | PIP5K1A | Q99755 | 2/20 | 0.46 |
| ▸ | BUB1 | O43683 | 3/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5813702 | 1.00 | MAPK10 (0.51) | MAPK10MAPK8MAPK14PIP5K1CPIK3CA | |
| SCHEMBL5814782 | 0.91 | MAPK10 (0.52) | MAPK10MAPK8MAPK14PIP5K1CPIK3CA | |
| SCHEMBL6830052 | 0.90 | MAPK10 (0.54) | MAPK10MAPK8MAPK14PIP5K1CPIK3CA | |
| SCHEMBL6830651 | 0.86 | MAPK10 (0.52) | MAPK10MAPK8MAPK14PIP5K1CPIK3CA | |
| SCHEMBL5814740 | 0.83 | MAPK10 (0.49) | MAPK10MAPK8MAPK14PIP5K1CPIK3CA | |
| SCHEMBL6505288 | 0.80 | BUB1 (0.49) | MAPK10MAPK8MAPK14PIP5K1CPIK3CA | |
| SCHEMBL1519020 | 0.72 | MAPK10 (0.76) | MAPK10MAPK8MAPK14PIP5K1CPIK3CA | |
| SCHEMBL1518802 | 0.72 | MAPK10 (0.69) | MAPK10MAPK8MAPK14PIP5K1CPIK3CA | |
| SCHEMBL1518956 | 0.71 | MAPK10 (0.78) | MAPK10MAPK8MAPK14PIP5K1CPIK3CA | |
| SCHEMBL6037695 | 0.69 | MAPK10 (0.62) | MAPK10MAPK8MAPK14PIP5K1CPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006104983-A1 | THERAPEUTIC METHODS FOR TYPE I DIABETES | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL (US) | 2006-10-05 | — | — | WO | disclosed |