Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 4/20 | 0.39 |
| ▸ | PPARD | Q03181 | 4/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | PPARA | Q07869 | 3/20 | 0.37 |
| ▸ | ICMT | O60725 | 6/20 | 0.35 |
| ▸ | THRA | P10827 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.34 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5809194 | 0.90 | THRA (0.41) | PLA2G2APPARDPPARGPPARAICMT | |
| SCHEMBL6601187 | 0.89 | PLA2G2A (0.49) | PLA2G2APPARDPPARGPPARAICMT | |
| SCHEMBL5812485 | 0.89 | LTB4R (0.34) | PLA2G2ATHRATHRBCYP26B1KMT2A | |
| SCHEMBL5812476 | 0.89 | LTB4R (0.34) | PLA2G2ATHRATHRBCYP26B1KMT2A | |
| SCHEMBL5813862 | 0.88 | LMNA (0.32) | PLA2G2ATHRATHRBKMT2AALDH1A1 | |
| SCHEMBL5810585 | 0.88 | PLA2G2A (0.41) | PLA2G2APPARDPPARGPPARAICMT | |
| SCHEMBL5811105 | 0.88 | POLB (0.35) | PLA2G2AICMTTHRATHRBMTNR1A | |
| SCHEMBL8624729 | 0.88 | THRA (0.46) | PLA2G2APPARDPPARGPPARAICMT | |
| SCHEMBL5810419 | 0.86 | PPARD (0.53) | PLA2G2APPARDPPARGPPARAICMT | |
| SCHEMBL6599833 | 0.85 | PLA2G2A (0.47) | PLA2G2APPARDPPARGPPARAICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006046683-A1 | THIAZOLYLBENZOFURAN DERIVATIVES AS LEUKOTRIENE AND PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | ASTELLAS PHARMA INC. (JP) | 2006-05-04 | — | — | WO | disclosed |