Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 2/20 | 0.47 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5100039 | 1.00 | MMP13 (0.47) | MMP13ADAM10MMP1MMP2MMP3 | |
| SCHEMBL3506148 | 0.95 | MMP13 (0.49) | MMP13ADAM10MMP1MMP2MMP3 | |
| SCHEMBL3506151 | 0.95 | MMP13 (0.49) | MMP13ADAM10MMP1MMP2MMP3 | |
| Trifluoroacetic Acid SCHEMBL5093630 | 0.84 | MMP13 (0.42) | MMP13ADAM10MMP1MMP2MMP3 | |
| SCHEMBL4585745 | 0.82 | ADAM10 (0.54) | MMP13ADAM10MMP1MMP2MMP3 | |
| SCHEMBL14138680 | 0.81 | ADAM10 (0.46) | MMP13ADAM10MMP1MMP2MMP3 | |
| SCHEMBL1682323 | 0.79 | OPRD1 (0.52) | OPRD1METTL3KDM1AALDH1A1PRMT5 | |
| SCHEMBL25650104 | 0.79 | OPRD1 (0.52) | OPRD1METTL3KDM1AALDH1A1PRMT5 | |
| SCHEMBL5100293 | 0.78 | MMP13 (0.44) | MMP13ADAM10MMP1MMP2MMP3 | |
| SCHEMBL5100301 | 0.78 | METTL3 (0.52) | OPRD1METTL3KDM1APDE7BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006038989-A1 | SUBSTITUTED ARYLAMIDES | CHEMOCENTRYX, INC. (US) | 2006-04-13 | — | — | WO | disclosed |