Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FUBP1 | Q96AE4 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5817989 | 0.83 | NPC1 (0.34) | KDM4ERAB9AMAPK1MEN1KMT2A | |
| SCHEMBL5813978 | 0.83 | KDM4E (0.38) | KDM4ERAB9AMAPK1MCHR1HTR7 | |
| SCHEMBL5816497 | 0.81 | PSD (0.39) | KDM4ERAB9AMEN1KMT2AMAPT | |
| SCHEMBL5820441 | 0.75 | ALDH1A1 (0.34) | ALDH1A1PTGS2 | |
| SCHEMBL4747261 | 0.69 | EGFR (0.46) | KDM4ERAB9AMAPK1SLC10A2MCHR1 | |
| SCHEMBL28127189 | 0.67 | TUBB1 (0.38) | RAB9AMAPK1MEN1KMT2AMAPT | |
| SCHEMBL5814749 | 0.65 | ADORA2A (0.35) | KDM4ERAB9AMEN1KMT2AMAPT | |
| SCHEMBL5818904 | 0.65 | ALDH1A1 (0.37) | KDM4EMAPK1MEN1KMT2AMAPT | |
| SCHEMBL5821178 | 0.65 | HIF1A (0.39) | KDM4EMAPK1MEN1KMT2AMAPT | |
| SCHEMBL28127427 | 0.62 | HSD17B3 (0.35) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006112666-A1 | PYRIDINE DERIVATIVES, METHODS OF THEIR PREPARATIONS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SK CHEMICALS CO., LTD. (KR) | 2006-10-26 | — | — | WO | disclosed |