Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5820441 | 0.91 | ALDH1A1 (0.34) | ALDH1A1GAA | |
| SCHEMBL5816497 | 0.90 | PSD (0.39) | NPC1RAB9ASMN1; SMN2MEN1LMNA | |
| SCHEMBL5815540 | 0.83 | KDM4E (0.42) | NPC1RAB9ASMN1; SMN2MEN1LMNA | |
| SCHEMBL5814749 | 0.81 | ADORA2A (0.35) | NPC1RAB9ASMN1; SMN2MEN1LMNA | |
| SCHEMBL4747882 | 0.68 | POLB (0.33) | ALDH1A1L3MBTL1POLBTHRBGAA | |
| SCHEMBL5813978 | 0.65 | KDM4E (0.38) | RAB9AMAPTALDH1A1KDM4EMAPK1 | |
| SCHEMBL4750005 | 0.64 | RAD51 (0.39) | NPC1RAB9ASMN1; SMN2MEN1LMNA | |
| SCHEMBL4795728 | 0.61 | MEN1 (0.34) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL4795580 | 0.61 | MEN1 (0.36) | NPC1RAB9ASMN1; SMN2MEN1LMNA | |
| SCHEMBL19862096 | 0.60 | MAOA (0.47) | NPC1RAB9ASMN1; SMN2MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006112666-A1 | PYRIDINE DERIVATIVES, METHODS OF THEIR PREPARATIONS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SK CHEMICALS CO., LTD. (KR) | 2006-10-26 | — | — | WO | disclosed |