Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 4/20 | 0.39 |
| ▸ | CDK4 | P11802 | 2/20 | 0.36 |
| ▸ | CCND1 | P24385 | 2/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5818904 | 0.84 | ALDH1A1 (0.37) | HIF1ATSHRPOLBALOX15LMNA | |
| SCHEMBL4749987 | 0.70 | EGFR (0.42) | HIF1APOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL28860292 | 0.67 | ALDH1A1 (0.63) | HIF1ATSHRPOLBALOX15LMNA | |
| SCHEMBL5815540 | 0.65 | KDM4E (0.42) | LMNANPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL5813978 | 0.65 | KDM4E (0.38) | ALDH1A1TP53KDM4EMAPTMAPK1 | |
| SCHEMBL7303075 | 0.65 | ALDH1A1 (0.65) | HIF1ATSHRPOLBLMNAMEN1 | |
| SCHEMBL12806441 | 0.59 | ALDH1A1 (0.56) | HIF1ACDK4CCND1TSHRALOX15 | |
| SCHEMBL20460064 | 0.59 | ALDH1A1 (0.48) | HIF1ATSHRPOLBALOX15LMNA | |
| SCHEMBL13913523 | 0.59 | ALDH1A1 (0.54) | HIF1ACDK4CCND1CCNE1CDK2 | |
| SCHEMBL2498677 | 0.58 | MEN1 (0.60) | HIF1APOLBLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006112666-A1 | PYRIDINE DERIVATIVES, METHODS OF THEIR PREPARATIONS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SK CHEMICALS CO., LTD. (KR) | 2006-10-26 | — | — | WO | disclosed |