Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 1/20 | 0.55 |
| ▸ | CTSS | P25774 | 4/20 | 0.54 |
| ▸ | CTSL | P07711 | 4/20 | 0.54 |
| ▸ | CTSB | P07858 | 2/20 | 0.54 |
| ▸ | CTSK | P43235 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13886178 | 0.85 | PSMB5 (0.61) | PSMB5CTSSCTSLCTSBCTSK | |
| SCHEMBL3119269 | 0.84 | CTSS (0.53) | CTSSCTSLCTSBCTSKL3MBTL1 | |
| SCHEMBL9825646 | 0.83 | CTSL (0.66) | PSMB5CTSSCTSLCTSBCTSK | |
| SCHEMBL23154438 | 0.82 | L3MBTL1 (0.68) | PSMB5CTSSCTSLCTSBCTSK | |
| SCHEMBL25000564 | 0.80 | MMP1 (0.63) | PSMB5MMP1MMP2MMP3MMP7 | |
| SCHEMBL25139508 | 0.80 | MMP1 (0.63) | PSMB5MMP1MMP2MMP3MMP7 | |
| SCHEMBL9826752 | 0.80 | CTSS (0.71) | CTSSCTSLCTSBCTSKHDAC8 | |
| SCHEMBL9826149 | 0.80 | CTSL (0.68) | CTSSCTSLCTSBCTSK | |
| SCHEMBL9825813 | 0.80 | CTSL (0.68) | CTSSCTSLCTSBCTSK | |
| SCHEMBL15692319 | 0.79 | PSMB5 (0.64) | PSMB5HDAC3HDAC4HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006105051-A2 | SYNTHESIS OF DIKETOPIPERAZINES | NEREUS PHARMACEUTICALS, INC. (US) | 2006-10-05 | — | — | WO | disclosed |