Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5823518 | 0.87 | G6PD (0.57) | G6PDALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL5818323 | 0.85 | G6PD (0.53) | G6PDALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL5818146 | 0.83 | G6PD (0.56) | G6PDALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL5821054 | 0.81 | G6PD (0.52) | G6PDALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL2947465 | 0.79 | G6PD (0.59) | G6PDALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL5817609 | 0.77 | MAPK13 (0.39) | ALDH1A1MEN1KMT2AHSD17B10GABRA1 | |
| SCHEMBL5820968 | 0.74 | CA2 (0.38) | KMT2A | |
| SCHEMBL5821476 | 0.74 | ALDH1A1 (0.43) | ALDH1A1MAPK1HPGDMAPTRAB9A | |
| SCHEMBL5823523 | 0.74 | G6PD (0.56) | G6PDALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL5821043 | 0.73 | ESR1 (0.35) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006129181-A2 | PREPARATION OF 4-PYRIMIDONE DERIVATIVES FOR TREATING INFLAMMATORY DISEASES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2006-12-07 | — | — | WO | disclosed |