SCHEMBL5820979

SCHEMBL5820979

C=CN(C(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 1/20 0.47
TDP1 Q9NUW8 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
ADRA2C P18825 1/20 0.42
TSHR P16473 2/20 0.42
KDM4E B2RXH2 2/20 0.41
KMT2A Q03164 2/20 0.41
NPSR1 Q6W5P4 1/20 0.40
ALDH1A1 P00352 3/20 0.39
CES2 O00748 2/20 0.39
CES1 P23141 2/20 0.39
DAO P14920 1/20 0.39
NAPRT Q6XQN6 1/20 0.39
LMNA P02545 1/20 0.39
MAPK1 P28482 1/20 0.39
HPGD P15428 2/20 0.39
NR3C2 P08235 1/20 0.38
MLYCD O95822 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6551359 0.88 CES2 (0.47) AKT1RAB9ASMN1; SMN2TSHRKDM4E
SCHEMBL15327833 0.84 HTT (0.57) TSHRKMT2AALDH1A1
SCHEMBL20679719 0.82 CRHBP (0.55) TDP1L3MBTL1SMN1; SMN2TSHRKMT2A
SCHEMBL14855512 0.82 TDP1 (0.47) AKT1TDP1L3MBTL1RAB9ASMN1; SMN2
SCHEMBL3257322 0.81 NPSR1 (0.44) AKT1TDP1L3MBTL1RAB9ASMN1; SMN2
SCHEMBL2390372 0.79 NPSR1 (0.43) AKT1TDP1L3MBTL1RAB9ATSHR
SCHEMBL6551914 0.78 AKT1 (0.41) AKT1TDP1L3MBTL1RAB9ASMN1; SMN2
SCHEMBL9560753 0.78 NPSR1 (0.41) AKT1TDP1L3MBTL1RAB9ASMN1; SMN2
SCHEMBL11883850 0.78 AKT1 (0.43) AKT1TDP1L3MBTL1RAB9ATSHR
SCHEMBL273919 0.78 KMT2A (0.46) AKT1L3MBTL1SMN1; SMN2TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115911342-A Silicon negative electrode material, preparation method thereof, negative electrode and lithium ion battery 江苏中兴派能电池有限公司 2023-04-04 CN disclosed
US-10933409-B2 Transition metal complex containing sulfonamide or amide group for olefin metathesis reaction and application thereof SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2021-03-02 US disclosed
US-10933409-B2 Transition metal complex containing sulfonamide or amide group for olefin metathesis reaction and application thereof SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2021-03-02 US disclosed
US-20190030521-A1 TRANSITION METAL COMPLEX CONTAINING SULFONAMIDE OR AMIDE GROUP FOR OLEFIN METATHESIS REACTION AND APPLICATION THEREOF SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2019-01-31 US disclosed
US-20190030521-A1 TRANSITION METAL COMPLEX CONTAINING SULFONAMIDE OR AMIDE GROUP FOR OLEFIN METATHESIS REACTION AND APPLICATION THEREOF SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2019-01-31 US disclosed
WO-2017135638-A1 TRANSITION METAL COMPLEX CONTAINING SULFONAMIDE OR AMIDE GROUP FOR OLEFIN DOUBLE DECOMPOSITION REACTION AND APPLICATION THEREOF 서울대학교산학협력단 2017-08-10 WO disclosed
EP-0931537-B1 A powder composition and a cosmetic composition containing said powder composition KOSE CORP (JP) 2006-08-02 EP disclosed
EP-1048457-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2004-12-15 EP disclosed
US-6455224-B1 SUPPORT WITH HYDROPHILIC SURFACE AND PHOTOSENSITIVE LAYER CONTAINING INFRARED ABSORBENT WHICH CHANGES FROM HYDROPHILIC TO HYDROPHOBIC BY HEAT AND HYDROPHILIC POLYMER HAVING FUNCTIONAL GROUP RENDERING LAYER WATER DEVELOPABLE FUJI PHOTO FILM CO., LTD. (JP) 2002-09-24 US disclosed
US-6379863-B1 LAMINATING HYDROPHOBIC POLYMER ON SUBSTRATE; HEATING TO MAKE HYDROPHILIC; DURABILITY; REDUCED BLEMISHES; STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 2002-04-30 US disclosed
EP-0562698-B1 Novel olefin/CO copolymers SHELL INT RESEARCH (NL) 1997-09-24 EP disclosed
EP-0446636-B1 External application base or auxiliary agent and external application composition for human being or animal containing the same SHOWA DENKO KK (JP) 1996-06-12 EP disclosed
US-5455042-A Ointment comprising a homogenous mixture of a polymer or copolymer of N-vinylacetamide, water and/or alcohols, and a pharmacologically active component SHOWA DENKO KABUSHIKI KAISHA (JP) 1995-10-03 US disclosed
US-5344655-A Drug delivery SHOWA DENKO K.K. (JP) 1994-09-06 US disclosed
US-5254338-A N-vinylacetamide polymer SHOWA DENKO K.K. (JP) 1993-10-19 US disclosed
EP-0562698-A1 Novel olefin/CO copolymers SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1993-09-29 EP disclosed
CN-1016697-B Process for preparing olefin/carbon monoxide copolymer SHELL INT RESEARCH (NL) 1992-05-20 CN disclosed
EP-0446636-A2 External application base or auxiliary agent and external application composition for human being or animal containing the same SHOWA DENKO KABUSHIKI KAISHA (JP) 1991-09-18 EP disclosed
US-4818811-A Terpolymer of carbon monoxide and ethylenically unsaturated monomers SHELL OIL COMPANY (US) 1989-04-04 US disclosed
CN-87107201-A Method for preparation of olefinlco copolymers 1988-06-15 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10933409-B2 Transition metal complex containing sulfonamide or amide group for olefin metathesis reaction and application thereof TST, NBAS, TRRAP AKT1 2690/4885TDP1 3385/4885L3MBTL1 4035/4885
US-20190030521-A1 TRANSITION METAL COMPLEX CONTAINING SULFONAMIDE OR AMIDE GROUP FOR OLEFIN METATHESIS REACTION AND APPLICATION THEREOF TST, NIT2, NBAS AKT1 3058/4885TDP1 4361/4885L3MBTL1 4207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.