Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13608371 | 0.81 | ENPP2 (0.47) | ENPP2TSHRTRPM8HDAC3HDAC1 | |
| SCHEMBL21303888 | 0.81 | ENPP2 (0.47) | ENPP2TSHRTRPM8CETP | |
| SCHEMBL2996280 | 0.80 | CETP (0.58) | ENPP2TSHRHPGDCETP | |
| SCHEMBL2991974 | 0.80 | CETP (0.58) | ENPP2TSHRHPGDCETP | |
| SCHEMBL11017199 | 0.76 | TSHR (0.59) | TSHRHPGDCETP | |
| SCHEMBL27042273 | 0.72 | FAAH (0.43) | ENPP2HPGDFAAH | |
| SCHEMBL1430472 | 0.70 | ALDH1A1 (0.59) | PSMD14HSP90AA1MMP2MC4RRAD52 | |
| SCHEMBL2615718 | 0.69 | ESR1 (0.63) | ENPP2PSMD14HSP90AA1MMP2MC4R | |
| SCHEMBL2615717 | 0.69 | ESR1 (0.63) | ENPP2PSMD14HSP90AA1MMP2MC4R | |
| SCHEMBL3941872 | 0.69 | ESR1 (0.63) | ENPP2PSMD14HSP90AA1MMP2MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006086609-A2 | INHIBITORS OF TRYPTASE | AXYS PHARMACEUTICALS, INC. (US) | 2006-08-17 | — | — | WO | disclosed |