Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1606039 | 0.76 | CYP17A1 (0.53) | ALDH1A1CYP19A1HPGD | |
| SCHEMBL27914051 | 0.71 | HSD11B1 (0.56) | HSD11B1ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL11647215 | 0.66 | HSD17B10 (0.48) | HSD11B1ALDH1A1KDM4EP2RX7 | |
| SCHEMBL8865912 | 0.66 | CYP19A1 (0.40) | ALDH1A1KDM4EP2RX7CYP19A1HPGD | |
| SCHEMBL11330557 | 0.66 | CYP19A1 (0.40) | ALDH1A1KDM4EP2RX7CYP19A1HPGD | |
| SCHEMBL11335494 | 0.66 | CYP19A1 (0.40) | ALDH1A1LMNAKDM4ECYP19A1 | |
| SCHEMBL11335498 | 0.66 | MGLL (0.38) | ALDH1A1LMNAKDM4ECYP19A1HPGD | |
| SCHEMBL11465836 | 0.65 | CYP19A1 (0.35) | ALDH1A1KDM4ECYP19A1HPGD | |
| SCHEMBL11475074 | 0.65 | CYP26A1 (0.45) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10455607 | 0.65 | CYP19A1 (0.64) | ALDH1A1CYP19A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005051871-A9 | IMPLANTABLE SENSORS AND IMPLANTABLE PUMPS AND ANTI-SCARRING AGENTS | ANGIOTECH INT AG (CH) | 2006-07-27 | — | — | WO | disclosed |
| WO-2006055008-A2 | IMPLANTABLE SENSORS AND IMPLANTABLE PUMPS AND ANTI-SCARRING AGENTS | ANGIOTECH INTERNATIONAL AG (CH) | 2006-05-26 | — | — | WO | disclosed |
| WO-2005046516-A2 | MEDICAL IMPLANTS AND ANTI-SCARRING AGENTS | ANGIOTECH INTERNATIONAL AG (CH) | 2005-05-26 | — | — | WO | disclosed |
| US-4243670-A | MICROBORICIDES; FUNGICIDES; SPORICIDES; HYGIENE | BAYER AKTIENGESELLSCHAFT (DE) | 1981-01-06 | — | — | US | disclosed |