Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 4/20 | 0.36 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5803212 | 0.92 | CHRNB2 (0.46) | CHRNB2CHRNA6CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL5802609 | 0.83 | FKBP1A (0.36) | CHRNB2CHRNA6 | |
| SCHEMBL8508770 | 0.83 | AKT1 (0.41) | CHRNB2CHRNA6CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL6235643 | 0.82 | CHRNB2 (0.52) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL8508512 | 0.82 | CHRNB2 (0.35) | CHRNB2CHRNA6CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7413499 | 0.82 | CHRNB4 (0.34) | CHRNB4CHRNA3 | |
| SCHEMBL5806257 | 0.82 | NPC1 (0.35) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL8508466 | 0.82 | CHRNB2 (0.33) | CHRNB2CHRNA6CHRNA4 | |
| SCHEMBL7404847 | 0.81 | CHRNA3 (0.33) | CHRNB2CHRNA6CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7412173 | 0.78 | CHRNB4 (0.40) | CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006086068-A1 | LABELED ALPHA-4-BETA-2 LIGANDS AND METHODS THEREFOR | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-08-17 | — | — | WO | disclosed |