Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7404847 | 0.88 | CHRNA3 (0.33) | CHRNB4CHRNA3 | |
| SCHEMBL5806257 | 0.87 | NPC1 (0.35) | CHRNB4CHRNA3 | |
| SCHEMBL5803212 | 0.83 | CHRNB2 (0.46) | CHRNB4CHRNA3 | |
| SCHEMBL7412173 | 0.83 | CHRNB4 (0.40) | CHRNB4CHRNA3 | |
| SCHEMBL8508045 | 0.82 | — | — | |
| SCHEMBL7415277 | 0.82 | CHRNB2 (0.32) | CHRNB4CHRNA3 | |
| SCHEMBL5822744 | 0.82 | CHRNB2 (0.36) | CHRNB4CHRNA3 | |
| SCHEMBL8585735 | 0.81 | NPC1 (0.37) | — | |
| SCHEMBL6232619 | 0.81 | NPC1 (0.37) | — | |
| SCHEMBL7410563 | 0.81 | CHRNB2 (0.38) | CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047690-A1 | HETEROCYCLIC ETHER AND THIOETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | Abbott Laboratories (US) | 2000-11-02 | — | — | EP | disclosed |
| WO-1999032480-A1 | HETEROCYCLIC ETHER AND THIOETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LABORATORIES (US) | 1999-07-01 | — | — | WO | disclosed |