Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.54 |
| ▸ | CA2 | P00918 | 14/20 | 0.50 |
| ▸ | CA1 | P00915 | 12/20 | 0.50 |
| ▸ | CA9 | Q16790 | 10/20 | 0.50 |
| ▸ | CA12 | O43570 | 8/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | CHUK | O15111 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547875 | 0.85 | CA2 (0.45) | PTGS2PTGS1CA2CA1CA9 | |
| SCHEMBL18118210 | 0.84 | CA2 (0.54) | CA2CA1CA9CA12MAOA | |
| SCHEMBL9151503 | 0.80 | LTA4H (0.46) | — | |
| SCHEMBL6986037 | 0.79 | EDNRB (0.56) | — | |
| SCHEMBL9510279 | 0.79 | HPGDS (0.58) | — | |
| SCHEMBL7408116 | 0.79 | BRD4 (0.41) | CA2CA1CA9CA12 | |
| SCHEMBL6026444 | 0.78 | BRD4 (0.43) | CA2CA1CA9CA12 | |
| SCHEMBL7408121 | 0.78 | HPGDS (0.44) | PTGS2CA2CA1CA9CA12 | |
| SCHEMBL1919495 | 0.77 | HPGDS (0.52) | — | |
| SCHEMBL28477141 | 0.76 | LTA4H (0.46) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006102898-A2 | OXAPROZIN OR A CLOSELY RELATED COMPOUND FOR THE TREATMENT OF ECZEMA | ASTION PHARMA A/S (DK) | 2006-10-05 | — | — | WO | disclosed |