Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7030199 | 0.84 | ALDH1A1 (0.50) | ALDH1A1LMNARAB9AGAANPSR1 | |
| SCHEMBL14268974 | 0.79 | TDP1 (0.41) | ALDH1A1RAB9ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5816221 | 0.79 | ALDH1A1 (0.41) | ALDH1A1LMNAAGTR1RAB9AGAA | |
| SCHEMBL13851862 | 0.78 | TDP1 (0.42) | ALDH1A1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL7027251 | 0.77 | MEN1 (0.45) | ALDH1A1RAB9AGAAMAPTMEN1 | |
| SCHEMBL8093014 | 0.77 | TSHR (0.49) | ALDH1A1MAPTKMT2A | |
| SCHEMBL7023148 | 0.77 | HTR1A (0.43) | ALDH1A1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL4870569 | 0.76 | HPGD (0.39) | ALDH1A1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL4871015 | 0.75 | TSHR (0.40) | ALDH1A1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL14268976 | 0.75 | HTR1A (0.44) | ALDH1A1RAB9AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006129257-A2 | KETOLIDE DERIVATIVES AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-12-07 | — | — | WO | disclosed |