Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7030199 | 0.81 | ALDH1A1 (0.50) | HTR1ATDP1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL5823359 | 0.77 | ALDH1A1 (0.45) | MAPTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL14696607 | 0.76 | L3MBTL1 (0.53) | L3MBTL1MAPTSMN1; SMN2TAAR1ALDH1A1 | |
| SCHEMBL27972864 | 0.76 | L3MBTL1 (0.48) | L3MBTL1TAAR1ALDH1A1 | |
| SCHEMBL7016796 | 0.76 | L3MBTL1 (0.45) | L3MBTL1MAPTTAAR1ALDH1A1 | |
| SCHEMBL661173 | 0.75 | QPCT (0.51) | MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL23772042 | 0.75 | BCHE (0.48) | TDP1L3MBTL1 | |
| SCHEMBL9730065 | 0.75 | L3MBTL1 (0.44) | L3MBTL1MAPTTAAR1ALDH1A1 | |
| SCHEMBL28281482 | 0.75 | L3MBTL1 (0.47) | L3MBTL1TAAR1ALDH1A1 | |
| SCHEMBL28281549 | 0.75 | L3MBTL1 (0.47) | L3MBTL1TAAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1026170-B1 | Erythromycin derivatives, their preparation and use as medicaments | AVENTIS PHARMA SA (FR) | 2003-01-15 | — | — | EP | disclosed |
| US-6313101-B1 | ANTIBIOTICS | AVENTIS PHARMA S.A. (FR) | 2001-11-06 | — | — | US | disclosed |
| EP-1026170-A1 | Erythromycin derivatives, their preparation and use as medicaments | HOECHST MARION ROUSSEL (FR) | 2000-08-09 | — | — | EP | disclosed |