Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 2/20 | 0.57 |
| ▸ | WNT3A | P56704 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | EDNRB | P24530 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8577219 | 0.86 | SMN1; SMN2 (0.48) | CTNNB1WNT3ARAB9ANPC1MAPT | |
| SCHEMBL4841835 | 0.85 | SRD5A2 (0.56) | CTNNB1WNT3ARAB9ANPC1MAPT | |
| SCHEMBL8301109 | 0.84 | RAB9A (0.61) | CTNNB1WNT3ARAB9ANPC1MAPT | |
| SCHEMBL4823544 | 0.82 | RAB9A (0.68) | CTNNB1WNT3ARAB9ANPC1MAPT | |
| SCHEMBL4823371 | 0.81 | CTNNB1 (0.78) | CTNNB1WNT3ARAB9ANPC1MAPT | |
| SCHEMBL3522633 | 0.81 | MAPT (0.60) | CTNNB1WNT3ARAB9ANPC1MAPT | |
| SCHEMBL8081475 | 0.80 | MAPT (0.65) | RAB9ANPC1MAPTALDH1A1LMNA | |
| SCHEMBL4821161 | 0.78 | CTNNB1 (0.61) | CTNNB1WNT3ARAB9ANPC1MAPT | |
| SCHEMBL2533157 | 0.76 | ALDH1A1 (0.67) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL31366495 | 0.76 | ALDH1A1 (0.67) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006032470-A1 | COMPOUNDS WHICH INCREASE APOLIPOPROTEIN A-1 PRODUCTION AND USES THEREOF IN MEDICINE | SMITHKLINE BEECHAM CORPORATION (US) | 2006-03-30 | — | — | WO | disclosed |