SCHEMBL5828547

SCHEMBL5828547

O=Cc1cc2cc([N+](=O)[O-])ccc2[nH]1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.55
CYP2A6 P11509 1/20 0.51
MAPT P10636 4/20 0.49
NOS1 P29475 2/20 0.49
POLB P06746 1/20 0.49
MAOB P27338 1/20 0.49
GRIA1 P42261 1/20 0.49
GRIA2 P42262 1/20 0.49
GRIA3 P42263 1/20 0.49
GRIA4 P48058 1/20 0.49
HRH4 Q9H3N8 1/20 0.45
CA12 O43570 1/20 0.44
CA9 Q16790 1/20 0.44
CRHBP P24387 1/20 0.44
CRHR2 Q13324 1/20 0.44
ERN1 O75460 1/20 0.44
ALDH1A1 P00352 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
IDO1 P14902 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11997383 0.87 CYP2A6 (0.51) CYP2A6MAPTNOS1POLBGRIA1
SCHEMBL14301819 0.82 PYGL (0.47) MAPTPOLBHRH4ALDH1A1LMNA
SCHEMBL28173938 0.79 CYP19A1 (0.58) CYP19A1MAPTNOS1POLBMAOB
SCHEMBL27848309 0.79 CYP19A1 (0.58) CYP19A1MAPTNOS1POLBMAOB
SCHEMBL1673078 0.79 CYP19A1 (0.76) CYP19A1MAPTNOS1POLBMAOB
SCHEMBL28389620 0.77 CYP19A1 (0.59) CYP19A1MAPTNOS1POLBMAOB
SCHEMBL5828903 0.76 CYP19A1 (0.51) CYP19A1MAPTNOS1POLBMAOB
SCHEMBL5828902 0.76 CYP19A1 (0.51) CYP19A1MAPTNOS1POLBMAOB
SCHEMBL30917347 0.76 CYP19A1 (0.60) CYP19A1CYP2A6MAPTNOS1POLB
SCHEMBL10172985 0.76 CYP19A1 (0.58) CYP19A1MAPTNOS1POLBMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775261-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2025-04-08 CN disclosed
CN-115427404-B Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2024-12-13 CN disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
EP-4139291-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF Anima Biotech Inc. (US) 2023-03-01 EP disclosed
CN-115427404-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2022-12-02 CN disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
WO-2021216665-A9 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-12-02 WO disclosed
WO-2021216665-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-10-28 WO disclosed
CN-102633778-B Synthesis method of anti-AIDS medicine delavirdine NANJING ACESYS PHARMACEUTICAL TECHNOLOGY CO LTD 2014-04-16 CN disclosed
CN-103342705-A Method for synthesizing pyrrole [1,2-a ] quinoxaline derivative NANJING UNIVERSITY OF TECHNOLOGY 2013-10-09 CN disclosed
CN-103333171-A Synthetic method of pyrrole [1,2-a ] quinoxaline derivative NANJING UNIVERSITY OF TECHNOLOGY 2013-10-02 CN disclosed
CN-102633778-A Synthesis method of anti-AIDS medicine delavirdine NANJING ACESYS PHARMACEUTICAL TECHNOLOGY CO LTD 2012-08-15 CN disclosed
US-7094798-B1 Inhibitors of checkpoint kinases (Wee1 and Chk1) PFIZER INC (US) 2006-08-22 US disclosed
EP-1501831-A1 INHIBITORS OF CHECKPOINT KINASES (WEE1 AND CHK1) WARNER-LAMBERT COMPANY LLC (US) 2005-02-02 EP disclosed
WO-2003091255-A1 INHIBITORS OF CHECKPOINT KINASES (WEE1 AND CHK1) WARNER-LAMBERT COMPANY LLC (US) 2003-11-06 WO disclosed
US-5866589-A Alkyl substituted piperadinyl and piperazinyl anti-AIDS compounds PHARMACIA & UPJOHN COMPANY (US) 1999-02-02 US disclosed
EP-0797576-A1 ALKYL SUBSTITUTED PIPERADINYL AND PIPERAZINYL ANTI-AIDS COMPOUNDS PHARMACIA & UPJOHN COMPANY (US) 1997-10-01 EP disclosed
WO-1996018628-A1 ALKYL SUBSTITUTED PIPERADINYL AND PIPERAZINYL ANTI-AIDS COMPOUNDS PHARMACIA & UPJOHN COMPANY (US) 1996-06-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF COL1A1, COL2A1, COL14A1 CYP19A1 4650/4885CYP2A6 3412/4885MAPT 3388/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.